Cost Plus Drugs Might Save Medicare Members Money — With a Catch

Cost Plus Drugs offers inexpensive generic prescription drugs, but it’s not a replacement for Medicare Part D coverage.
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Written by Alex Rosenberg
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Edited by Holly Carey
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Nerdy takeaways
  • Cost Plus Drugs sells generic medications online with transparent and often inexpensive pricing.

  • Medicare prescription drug plans won’t pay for Cost Plus Drugs medications, so you’d have to pay out of pocket.

  • It’s worth comparing prices to see where you can fill your prescription cheapest.

  • You should maintain Medicare Part D coverage to avoid a late enrollment penalty, even if you fill some prescriptions through Cost Plus Drugs.

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Cost Plus Drugs offers low-cost generic prescription drugs with a transparent pricing system. Generic medications and their prices are listed on the company’s website. After your doctor sends a prescription to Cost Plus Drugs, you check out online and the medications are shipped to you.

Cost Plus Drugs can offer significant savings on certain prescription drugs, but there are some downsides, too — particularly for people with Medicare. Here’s what Medicare beneficiaries should know about this online pharmacy.

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What is Cost Plus Drugs?

The Mark Cuban Cost Plus Drug Co., or Cost Plus Drugs, is an online pharmacy for generic medications. The company, which launched in January 2022, takes its name from investor Mark Cuban, a billionaire entrepreneur and philanthropist.

The company lists nearly 1,000 generic medications for sale on its website, and has been adding more over time. It doesn’t sell any brand-name drugs or specialty drugs.

Cost Plus Drugs is notable for offering cheap medications with transparent pricing. “Every product we sell is priced exactly the same way: our cost plus 15%, plus the pharmacy fee, if any,” the company's website says about its pricing model.

Cost Plus Drugs offers this example for a 30-count supply of 400 milligrams of Imatinib, a cancer drug:

  • Manufacturing cost: $31.20.

  • 15% markup: $4.80 (rounded per pill).

  • Pharmacy labor (the “pharmacy fee”): $5.

  • Shipping: $5.

Including the shipping, that would be $46 per month.

This price offers savings of more than $9,600 versus other companies’ retail prices, the company says. That comparison is probably based on brand-name Gleevec, which can cost $10,000 or more per month at retail.

Generic Imatinib is much cheaper, but can still cost well over $100 per month from major retail pharmacies, even when covered by a Medicare prescription drug plan.

Does Cost Plus Drugs work with Medicare?

“We are cheaper than Medicare copays, so we are a great place for Medicare recipients to buy medications,” Mark Cuban wrote in a Twitter direct message.

If you want to buy those lower-cost medications from Cost Plus Drugs, your Medicare plan won’t be involved. Cost Plus Drugs doesn’t bill Medicare, whether you have a stand-alone Medicare Part D plan or a Medicare Advantage plan with prescription drug coverage. You’d have to pay for medications from Cost Plus Drugs out of your own pocket, but it may be well worth doing.

How Cost Plus Drugs affects your Medicare Part D coverage

You don’t get any credit toward your Part D deductible when you fill a prescription through Cost Plus Drugs. You only meet the Part D deductible by paying for drugs your plan is covering, and Cost Plus Drugs doesn’t bill Medicare Part D plans.

You can still meet your Medicare Part D deductible by paying for other drugs your plan covers. For example, Cost Plus Drugs doesn’t sell brand-name drugs, so you could fill brand-name prescriptions through your Part D plan and meet the deductible that way.

If you fill most or all of your prescriptions through Cost Plus Drugs, though, you’re potentially missing out on a lot of credit toward your deductible. You still have to pay your premiums, but until you hit the deductible, your Medicare Part D plan doesn’t pay for your drugs.

The Medicare Part D penalty

If you take mostly or entirely generic drugs, it might be tempting to use Cost Plus Drugs and go without Medicare Part D coverage. However, you could face the Medicare Part D late enrollment penalty. You’ll need to have either Medicare Part D or another kind of creditable coverage (such as an employer plan) that’s at least as good as Medicare Part D to avoid being penalized.

Even if you could save money by using Cost Plus Drugs and skipping Medicare Part D, you’d face the Part D penalty if you ever sign up (or sign back up) for Medicare Part D.

The Medicare Part D late enrollment penalty is 1% of the national base beneficiary premium — $34.70 in 2024 — for each full month that you didn’t have qualifying prescription drug coverage, rounded to the nearest 10 cents.

For example, if you went without coverage for two years, or 24 months, your monthly penalty would be 24% of $34.70, or $8.30 (rounded to the nearest 10 cents), in 2024. That amount is added to your premiums every month. It would go up or down in subsequent years based on the national base beneficiary premium, but it doesn’t ever go away.

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Could Cost Plus Drugs partner with Medicare?

Cost Plus Drugs isn’t entirely opposed to working with insurance companies. As of June 2024, the company lists 12 prescription insurance plans it accepts — up from just one in early 2023. Its website says “we will be adding more insurance plans in the coming months.”

Cuban described the company in a Twitter direct message as “willing and able to integrate” with government programs like Medicare, and added “but we have not had those discussions yet.”

If Medicare or Medicare Advantage companies made agreements with Cost Plus Drugs, it could seriously shake up drug pricing. “If we could sell to Medicare, we could save taxpayers tens of billions of dollars,” Cuban wrote.

A 2022 study published in the Annals of Internal Medicine estimates that Medicare could have saved about $3.3 billion in 2020 if it had bought a subset of drugs available from Cost Plus Drugs at the company’s rates. (For context, the total Medicare Part D budget for fiscal year 2020 was about $89 billion, according to the Congressional Budget Office.)

Is Cost Plus Drugs a good idea for Medicare beneficiaries?

Medicare beneficiaries had an average of 54 prescriptions per year as of 2018, according to data analysis by the Congressional Budget Office. In the data, one prescription equals a 30-day supply, so that’s about 4.5 prescription fills per month. Saving money on even a portion of those could be a big deal for Medicare beneficiaries.

Cost Plus Drugs could be a good option for potential savings on generic drugs, even for people who already have other Medicare prescription drug coverage.

However, there are also some Medicare-specific downsides to Cost Plus Drugs. Note these additional considerations:

  • Prescriptions filled through Cost Plus Drugs don’t count toward the Medicare Part D deductible.

  • Cost Plus Drugs doesn’t sell brand-name drugs (which tend to be the most expensive).

  • You’d owe steep and permanent penalties for going without Medicare Part D coverage, so it’s not a good idea to drop your Part D plan, even if you can get cheaper medication from Cost Plus Drugs.

In short, if you take a drug with a generic version, it’s worth checking the price on Cost Plus Drugs to see whether you could potentially save money. But Cost Plus Drugs isn’t a replacement for Medicare Part D, so take care not to run afoul of penalties that could add up to more than you save on prescriptions.

This article was written with the support of a journalism fellowship from The Gerontological Society of America, The Journalists Network on Generations and The Silver Century Foundation.

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