21 Best-Performing Small-Cap Stocks for October 2026

Small-cap stocks can bring diversification and higher growth potential — albeit with higher risks — to a portfolio. Here's what to know before investing.

Anna-Louise Jackson
Robert Beaupre
Updated
Investors salivate over the biggest companies in the market — the likes of Apple, Google and Amazon — but where’s the love for the market’s perpetual underdogs: small-cap stocks?
When these investments do get some time in the limelight, it’s often for unflattering reasons — violent price swings or fraudulent activity, for example. Small caps can diversify portfolios and bring higher growth potential — albeit with higher risks.

What are small-cap stocks?

Small-cap stocks are company shares with market values between $250 million and $2 billion, though that range isn't universal. "Cap" is shorthand for market capitalization, or the total number of a company’s shares multiplied by its current stock price.
The definition of small when it comes to stocks is subjective. The Russell 2000 Index, the first benchmark of small-cap stocks, is the best-known gauge. The market caps of its member companies currently range from about $240 million to $6 billion. The other major indexes tracking these stocks — the Standard & Poor’s SmallCap 600 and the MSCI USA Small Cap Index — include U.S. companies with even broader ranges of market caps.

Small-cap stocks vs. mid-cap and large-cap stocks

Again, definitions can vary, but here is the breakdown of small-cap stocks versus mid-cap and large-cap stocks, according to the Financial Industry Regulatory Authority (FINRA):
  • Small-cap stocks: Public companies valued at $250 million to $2 billion.
  • Mid-cap stocks: Companies whose market capitalization is more than $2 billion but less than $10 billion.
  • Large-cap stocks: Companies worth $10 billion or more. 

Best small-cap stocks, ordered by one-year performance

Below is a table of the 21 best-performing stocks that are listed on major U.S. exchanges and have a market cap under $10 billion, ordered by one-year returns.
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The best-performing small cap stock by one-year return is Eloxx Pharmaceuticals Inc (ELOX), which is up 1364445.51%.
Ticker
Company
Performance (Year)
ELOX
Eloxx Pharmaceuticals Inc
1364445.51%
MGRT
Mega Fortune Co Ltd
2110.07%
AXTI
AXT Inc
1504.68%
NVA
Nova Minerals Corp
1277.05%
ANL
Adlai Nortye Group Ltd ADR
778.89%
SLS
SELLAS Life Sciences Group Inc
613.60%
IOVA
Iovance Biotherapeutics Inc
575.57%
ERAS
Erasca Inc
562.90%
ANRO
Alto Neuroscience Inc
534.63%
KOD
Kodiak Sciences Inc
532.72%
DMRA
Damora Therapeutics Inc
501.16%
MTC
Mmtec Inc
500.35%
CYPH
Cypherpunk Technologies Inc
494.94%
CLYM
Climb Bio Inc
488.32%
MXL
MaxLinear Inc
462.35%
SPRB
Spruce Biosciences Inc
456.97%
SYRE
Spyre Therapeutics Inc
444.98%
PRAX
Praxis Precision Medicines Inc
444.77%
TJGC
TJGC Group Ltd
435.07%
OPTX
Syntec Optics Holdings Inc
407.64%
IMMX
Immix Biopharma Inc
386.54%
Source: Finviz. Data is current as of October 1, 2026, and is intended for informational purposes only.
Small caps historically have a relatively high correlation — meaning they tend to move in lockstep — with large-cap stocks. But which group is performing better than the other over a given time frame fluctuates regularly, based on factors such as macroeconomic growth and politics.

Why small-cap stocks are risky

As small-cap businesses expand, their stocks offer a higher growth potential compared with larger companies. But that comes with a greater risk of volatility — including more (and bigger) fluctuations in stock prices and earnings reports. This trade-off is known as the risk premium.
Small-cap stocks can also be more fertile territory for fraudulent activity.

Why small-cap stocks are appealing

The sheer number of small-cap stocks means there’s a plethora of options for investing in them. What’s more, the proliferation of exchange-traded funds has made it easier to buy a basket of stocks with a specific investing strategy — growth or value, for example. Small caps can be an under-appreciated — or even overlooked — way to add diversification to your portfolio.

Why small-cap stocks are not that different

It’s important to know what makes small-cap stocks distinctive, but you shouldn’t necessarily obsess over the differences. They have a lot in common with the others that might be in your portfolio: They trade on exchanges, their prices are published intraday, Wall Street analysts write research reports about them, and by virtue of being public, these companies must disclose a wealth of information to investors.
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